{"product_id":"hes7-antibody-hairy-and-enhancer-of-split-related-protein-7-bha17135027","title":"HES7 Antibody \/ Hairy and enhancer of split-related protein 7","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eHES7 Antibody \/ Hairy and enhancer of split-related protein 7 is an antibody targeting \u003cstrong\u003eHES7\u003c\/strong\u003e. Host: \u003cstrong\u003eRabbit\u003c\/strong\u003e. Polyclonal. Format: Lyophilized. Applications: WB, ELISA.\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTarget:\u003c\/strong\u003e HES7.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunogen:\u003c\/strong\u003e E.coli-derived human HES7 recombinant protein (Position: D26-R172) was used as the immunogen for the HES7 antibody..\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpecies reactivity:\u003c\/strong\u003e Human, Mouse, Rat.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConjugate:\u003c\/strong\u003e Unconjugated (no label listed).\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background (from provided description)\u003c\/h2\u003e\u003cp\u003eHES7 antibody detects Hairy and enhancer of split-related protein 7, encoded by the HES7 gene on chromosome 17p13.1. HES7 is a basic helix-loop-helix (bHLH) transcriptional repressor and part of the HES family of Notch effectors. It plays a crucial role in the segmentation clock during somitogenesis, regulating cyclic gene expression that establishes somite boundaries in vertebrate embryos.\u003c\/p\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\u003cli\u003e\n\u003cstrong\u003eWB:\u003c\/strong\u003e relative abundance and band pattern assessment using appropriate controls.\u003c\/li\u003e\u003c\/ul\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eAccount for isoforms, paralogs, and post-translational modifications when interpreting signal.\u003c\/li\u003e\n\u003cli\u003eSupport specificity with biological controls (e.g., KO\/KD where available) and technical controls (e.g., secondary-only\/isotype).\u003c\/li\u003e\n\u003c\/ul\u003e\u003c!-- Sources (internal): - UniProt Knowledgebase (UniProt) – https:\/\/www.uniprot.org\/ - NCBI Gene (NIH\/NLM) – https:\/\/www.ncbi.nlm.nih.gov\/gene\/ - ZFIN – https:\/\/zfin.org\/ - Ensembl – https:\/\/www.ensembl.org\/ - Nature Methods (2015): A proposal for validation of antibodies – https:\/\/www.nature.com\/articles\/nmeth.3230 --\u003e","brand":"NSJ Bioreagents","offers":[{"title":"Adding 0.2 ml of distilled water will yield a concentration of 500 ug\/ml \/ 100 ug","offer_id":53046716957037,"sku":"FY12124","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/get_image_2408f004-c50c-4fd4-a531-ebec07cb6a16.jpg?v=1782236963","url":"https:\/\/www.ebiohippo.com\/products\/hes7-antibody-hairy-and-enhancer-of-split-related-protein-7-bha17135027","provider":"BioHippo","version":"1.0","type":"link"}