{"product_id":"hexetidine-bhb21902669","title":"Hexetidine","description":"\u003cdiv class=\"bhp-desc\"\u003e\n\u003cstyle\u003e.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}.bhp-desc p{margin:0 0 12px}.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}.bhp-desc .bhp-cat-pill{display:inline-block;background:#003366;color:#fff;border-radius:20px;padding:3px 12px;font-size:13px;margin-bottom:10px}\u003c\/style\u003e\n\u003cspan class=\"bhp-cat-pill\"\u003eBioactive Small Molecules\u003c\/span\u003e\u003ch2\u003eCompound Overview\u003c\/h2\u003e\n\u003cp\u003eHexetidine, also known as NSC-17764, is an orally active antibacterial and antifungal agent with broad antibacterial and antifungal activity. Combined with IPBC, it potentiates strong fungal growth inhibition, and at concentrations greater than 0.1% it can cause oral ulceration. It also improves plaque-inhibiting activity when combined with zinc and has shown effectiveness on purulent wounds when combined with ultrasound, making it a promising candidate for research on fungus-related diseases and soft-tissue purulent inflammation\u003csup\u003e[1][2][3][4][5]\u003c\/sup\u003e. It is supplied as a colorless to light yellow liquid (C21H45N3, MW 339.60) at 98.0% purity.\u003c\/p\u003e\n\u003ch2\u003ePhysical \u0026amp; Chemical Properties\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eCAS Number\u003c\/th\u003e\n\u003ctd\u003e141-94-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eMolecular Formula\u003c\/th\u003e\n\u003ctd\u003eC21H45N3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eMolecular Weight\u003c\/th\u003e\n\u003ctd\u003e339.60 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003ePurity\u003c\/th\u003e\n\u003ctd\u003e98.0%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eAppearance\u003c\/th\u003e\n\u003ctd\u003eLiquid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eColor\u003c\/th\u003e\n\u003ctd\u003eColorless to light yellow\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eDensity\u003c\/th\u003e\n\u003ctd\u003e0.889 g\/cm3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSMILES\u003c\/th\u003e\n\u003ctd\u003eNC1(C)CN(CC(CC)CCCC)CN(CC(CC)CCCC)C1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSignaling Pathway\u003c\/th\u003e\n\u003ctd\u003eAnti-infection\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSolubility\u003c\/th\u003e\n\u003ctd\u003eIn Vitro: DMSO: 200 mg\/mL (588.93 mM; Requires sonication and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)\u003cbr\u003eEthanol: 100 mg\/mL (294.46 mM; Requires sonication)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStorage\u003c\/th\u003e\n\u003ctd\u003ePure form: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eShipping\u003c\/th\u003e\n\u003ctd\u003eRoom temperature in continental US; may vary elsewhere.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003ch2\u003eLiterature Cited\u003c\/h2\u003e\n\u003cp style=\"font-size:14px;color:#555;margin:0 0 10px\"\u003e\u003cem\u003eSources cited in this description and in the In Vitro \u0026amp; In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e [1]. \u003ca target=\"_blank\" rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33738552\/\"\u003eVallières C, et al. Potentiated inhibition of Trichoderma virens and other environmental fungi by new biocide combinations[J]. Appl Microbiol Biotechnol. 2021 Apr;105(7):2867-2875.\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e [2]. Dr. Sandhya Gnanasambandam, et al. Role of supra-gingival plaque in the pathophysiology of periodontitis. World Journal of Pharmaceutical Research. 2024 April 12; 13(8): 902-915.\u003c\/p\u003e\n\u003cp\u003e [3]. \u003ca target=\"_blank\" rel=\"noopener\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21356020\"\u003eAfennich F, et al. The effect of hexetidine mouthwash on the prevention of plaque and gingival inflammation: a systematic review. Int J Dent Hyg. 2011 Aug;9(3):182-90.\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e [4]. Ivan S. Dragovoz, et al. Comparative Evaluation of Isolated and Complex Use of Hexetidine and Photoditazine in Combination with Ultrasound Therapy in the Treatment of Purulent Wounds under Experimental Conditions[J]. International Journal of Biomedicine. 2022 March 20; 12(1):138-141\u003c\/p\u003e\n\u003cp\u003e [5]. \u003ca target=\"_blank\" rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11545308\/\"\u003eGorman SP, et al. The concomitant development of poly(vinyl chloride)-related biofilm and antimicrobial resistance in relation to ventilator-associated pneumonia[J]. Biomaterials. 2001 Oct;22(20):2741-7. \u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003eSafety\u003c\/h2\u003e\n\u003cdiv class=\"bhp-warning-box\"\u003e\u003cp\u003e\u003cstrong\u003eFor Research Use Only.\u003c\/strong\u003e Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.\u003c\/p\u003e\u003c\/div\u003e\n\u003c\/div\u003e","brand":"MedChemExpress (MCE)","offers":[{"title":"25 mg","offer_id":67604963623277,"sku":"HY-B0996-25MG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"50 mg","offer_id":67605438300525,"sku":"HY-B0996-50MG","price":96.0,"currency_code":"USD","in_stock":true},{"title":"100 mg","offer_id":67605438333293,"sku":"HY-B0996-100MG","price":144.0,"currency_code":"USD","in_stock":true},{"title":"500 mg","offer_id":67605438366061,"sku":"HY-B0996-500MG","price":336.0,"currency_code":"USD","in_stock":true},{"title":"1 g","offer_id":67605438398829,"sku":"HY-B0996-1G","price":0.0,"currency_code":"USD","in_stock":true},{"title":"5 g","offer_id":67605438431597,"sku":"HY-B0996-5G","price":0.0,"currency_code":"USD","in_stock":true},{"title":"1 mL x 10 mM (in DMSO)","offer_id":67605438464365,"sku":"HY-B0996-1MLX10MM","price":66.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/hy-b0996.gif?v=1790973103","url":"https:\/\/www.ebiohippo.com\/products\/hexetidine-bhb21902669","provider":"BioHippo","version":"1.0","type":"link"}