{"product_id":"human-abl-interactor-1-abi1-elisa-kit-bhe13703084","title":"Human Abl interactor 1 (ABI1) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Abl interactor 1 (ABI1) ELISA Kit has high sensitivity and excellent specificity for detection of Human ABI1. No significant cross-reactivity or interference between Human ABI1 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eABI1 has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac. In addition, the encoded protein may play a role in the regulation of EGF-induced Erk pathway activation as well as cytoskeletal reorganization and EGFR signaling.\u003c\/p\u003e\u003cp\u003eAbi1 is adoptor protein. It interacts with c-Abl and WAVE2 which is actin polymerization regulator. It is known that Abi1 enhances the phosphorylation of WAVE2 by c-Abl. The phosphorylation of c-Abl promotes actin polymerization.Furthermore, Abi1 is component of WAVE complex. Some research paper showed that knock down of Abi1 by si(short interffering)RNA promoted degradation of WAVE complex proteins.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338612892013,"sku":"KTE60868-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338760413549,"sku":"KTE60868-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338760446317,"sku":"KTE60868-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338760479085,"sku":"KTE60868-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60868.png?v=1778954707","url":"https:\/\/www.ebiohippo.com\/products\/human-abl-interactor-1-abi1-elisa-kit-bhe13703084","provider":"BioHippo","version":"1.0","type":"link"}