{"product_id":"human-b-cell-activation-factor-from-the-tumor-necrosis-factor-family-receptor-baff-r-elisa-kit-bhe13702439","title":"Human B cell activation factor from the tumor necrosis factor family receptor (BAFF-R) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman B cell activation factor from the tumor necrosis factor family receptor (BAFF-R) ELISA Kit has high sensitivity and excellent specificity for detection of Human TNFRSF13C. No significant cross-reactivity or interference between Human TNFRSF13C and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eB cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. B cell activation factor from the tumor necrosis factor family receptor (BAFF-R) is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338592084333,"sku":"KTE60221-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338697433453,"sku":"KTE60221-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338697466221,"sku":"KTE60221-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338697498989,"sku":"KTE60221-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60221.png?v=1778954636","url":"https:\/\/www.ebiohippo.com\/products\/human-b-cell-activation-factor-from-the-tumor-necrosis-factor-family-receptor-baff-r-elisa-kit-bhe13702439","provider":"BioHippo","version":"1.0","type":"link"}