{"product_id":"human-bivalirudin-bhp11002666","title":"Human Bivalirudin","description":"\u003cp\u003e\u003cstrong\u003eHuman Bivalirudin\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eBivalirudin directly inhibits thrombin by specifically binding as well to the catalytic site and to the anion-binding exosite of circulating and clot-bound thrombin. Bivalirudin is a specific and reversible direct thrombin inhibitor. Thrombin, which is a serine protease, plays a central role in the thrombotic process; it cleaves fibrinogen into fibrin monomers and activates Factor XIII to Factor XIIIa, allowing fibrin to develop a covalently cross-linked structure which stabilizes the thrombus. Thrombin also activates Factors V and VIII, which promotes further thrombin generation, activates platelets, stimulating aggregation and granule release.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"1 mg","offer_id":53038087766381,"sku":"pro-357-1MG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"5 mg","offer_id":53038358167917,"sku":"pro-357-5MG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100 mg","offer_id":53038358200685,"sku":"pro-357-100MG","price":500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-bivalirudin-PRO-357.png?v=1782158209","url":"https:\/\/www.ebiohippo.com\/products\/human-bivalirudin-bhp11002666","provider":"BioHippo","version":"1.0","type":"link"}