{"product_id":"human-canalicular-multispecific-organic-anion-transporter-1-abcc2-elisa-kit-bhe13703075","title":"Human Canalicular multispecific organic anion transporter 1 (ABCC2) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Canalicular multispecific organic anion transporter 1 (ABCC2) ELISA Kit has high sensitivity and excellent specificity for detection of Human ABCC2. No significant cross-reactivity or interference between Human ABCC2 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eABCC2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR\/TAP, MRP, ALD, OABP, GCN20, White).his protein is a member of the MRP subfamily, which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells.Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338612728173,"sku":"KTE60859-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338760020333,"sku":"KTE60859-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338760053101,"sku":"KTE60859-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338760085869,"sku":"KTE60859-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60859.png?v=1778954700","url":"https:\/\/www.ebiohippo.com\/products\/human-canalicular-multispecific-organic-anion-transporter-1-abcc2-elisa-kit-bhe13703075","provider":"BioHippo","version":"1.0","type":"link"}