{"product_id":"human-cell-cycle-control-protein-50a-tmem30a-elisa-kit-bhe13702498","title":"Human Cell cycle control protein 50A (TMEM30A) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Cell cycle control protein 50A (TMEM30A) ELISA Kit has high sensitivity and excellent specificity for detection of Human TMEM30A. No significant cross-reactivity or interference between Human TMEM30A and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eAntitumor alkylphospholipids initiate apoptosis in transformed HL-60 and Jurkat cells while sparing their progenitors. 1-O-Alkyl-2-carboxymethyl-sn-glycero-3-phosphocholine (Edelfosine) like other short-chained phospholipids--inflammatory platelet-activating factor (PAF) and apoptotic oxidatively truncated phospholipids--are proposed to have intracellular sites of action, yet a conduit for these choline phospholipids into mammalian cells is undefined. Edelfosine is also accumulated by Saccharomyces cerevisiae in a process requiring the membrane protein Lem3p, and the human genome contains a Lem3p homolog TMEM30a. Import of choline phospholipids into S. cerevisiae ΔLem3 is partially reconstituted by human TMEM30a and by Lem3p-TMEM30a chimeras, showing the proteins are orthologous.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338593198445,"sku":"KTE60280-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338701955437,"sku":"KTE60280-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338701988205,"sku":"KTE60280-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338702020973,"sku":"KTE60280-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60280.png?v=1778954642","url":"https:\/\/www.ebiohippo.com\/products\/human-cell-cycle-control-protein-50a-tmem30a-elisa-kit-bhe13702498","provider":"BioHippo","version":"1.0","type":"link"}