{"product_id":"human-collectrin-tmem27-elisa-kit-bhe13702499","title":"Human Collectrin (TMEM27) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Collectrin (TMEM27) ELISA Kit has high sensitivity and excellent specificity for detection of Human TMEM27. No significant cross-reactivity or interference between Human TMEM27 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eTMEM27 encodes a transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. TMEM27 has an N-terminal signal sequence, followed by a noncatalytic extracellular domain, a transmembrane segment, and a cytosolic domain. The extracellular domain contains an O-glycosylation site and 2 N-glycosylation sites. Human TMEM27 shares 47.8% identity with the C-terminal end of ACE2, but it lacks an ACE2-like catalytic domain. Northern blot analysis of rat, mouse, and human tissues detected a transcript of about 1.8 kb exclusively in kidney.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338593919341,"sku":"KTE60281-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338703626605,"sku":"KTE60281-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338703659373,"sku":"KTE60281-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338703692141,"sku":"KTE60281-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60281.png?v=1778954644","url":"https:\/\/www.ebiohippo.com\/products\/human-collectrin-tmem27-elisa-kit-bhe13702499","provider":"BioHippo","version":"1.0","type":"link"}