{"product_id":"human-complement-c3d-bhp11006022","title":"Human Complement C3d","description":"\u003cp\u003e\u003cstrong\u003eHuman Complement C3d\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eC3d is derived from human C3 after a series of proteolytic cleavages.C3d is prepared from purified human C3. The C3 is converted to C3b by treatment with the natural human C3 convertase and this C3b is converted to iC3b. Finally, this iC3b is cleaved with trypsin to yield C3d.If the C3b precursor was attached to a surface (as occurs during complement activation) the iC3b, C3dg and C3d fragments would remain covalently attached to that surface.C3d is able to attach to a surfaceonly during complement activation on a surface. Surface-bound C3d is linked to the target through an ester or an amide covalent bond. Ester bonds are unstable, thusC3d releasesfrom the particle.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e\n\u003ch3\u003eActivity \u0026amp; assay information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHuman Virus Test:\u003c\/strong\u003e Plasma from each donor has been tested and found negative for antibody to HIV-1, HIV-2, HCV and HBSAG.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"10 ug","offer_id":53038181351789,"sku":"pro-2687-10UG","price":385.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53038540521837,"sku":"pro-2687-50UG","price":1045.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53038540554605,"sku":"pro-2687-100UG","price":1650.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-c3d-human-PRO-2687.png?v=1782158390","url":"https:\/\/www.ebiohippo.com\/products\/human-complement-c3d-bhp11006022","provider":"BioHippo","version":"1.0","type":"link"}