{"product_id":"human-complement-c4b-bhp11006026","title":"Human Complement C4b","description":"\u003cp\u003e\u003cstrong\u003eHuman Complement C4b\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eC4b is derived from native C4 upon cleavage and release of C4a. 4b is created by cleavage of purified C4 with the classical pathway activated protease C1s enzyme. C4b is essential to the function of 2 of the 3 pathways of complement. Both the classical and lectin pathways of complement activation generate surface-bound active proteases that cleave C4. These enzymes cleave a peptide bond in C4 releasing the anaphylatoxin C4a and activating C4b. C4A and C4B are 2 variants of C4 that are common in man whereas, in animals who have only 1 type usually have C4B.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e\n\u003ch3\u003eActivity \u0026amp; assay information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHuman Virus Test:\u003c\/strong\u003e Plasma from each donor has been tested and found negative for antibody to HIV-1, HIV-2, HCV and HBSAG\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"20 ug","offer_id":53038180991341,"sku":"pro-2690-20UG","price":220.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53038541767021,"sku":"pro-2690-100UG","price":660.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038541799789,"sku":"pro-2690-1MG","price":3500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-c4b-human-PRO-2690.png?v=1782158390","url":"https:\/\/www.ebiohippo.com\/products\/human-complement-c4b-bhp11006026","provider":"BioHippo","version":"1.0","type":"link"}