{"product_id":"human-complement-c5a-bhp11006028","title":"Human Complement C5a","description":"\u003cp\u003e\u003cstrong\u003eHuman Complement C5a\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eComplement Component C5a (C5a) is involved in the complement system and it is encoded by the C5 gene in human. Complement C5 is cleaved into C5a and C5b. C5a has an imperative role in chemotaxis and C5b forms the 1st part of the complement membrane attack complex. Complement C5 is the 5th component of complement, which plays a central role in inflammatory and cell killing processes. C5a protein is composed of alpha and beta polypeptide chains, which are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin, which has potent spasmogenic and chemotactic activity, is derivative from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product forms a complex with the C6 complement component, and this complex is the basis for creation of the membrane attack complex, which includes supplementary complement components.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e\n\u003ch3\u003eActivity \u0026amp; assay information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHuman Virus Test:\u003c\/strong\u003e Plasma from each donor has been tested and found negative for antibody to HIV-1, HIV-2, HCV, HTLV-I \u0026amp;II, STS and HBSAG.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"1 ug","offer_id":53038180368749,"sku":"pro-2692-1UG","price":110.0,"currency_code":"USD","in_stock":true},{"title":"5 ug","offer_id":53038541701485,"sku":"pro-2692-5UG","price":440.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53038541734253,"sku":"pro-2692-50UG","price":1950.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-complement-c5a-PRO-2692.png?v=1782158390","url":"https:\/\/www.ebiohippo.com\/products\/human-complement-c5a-bhp11006028","provider":"BioHippo","version":"1.0","type":"link"}