{"product_id":"human-complement-component-c4c-bhp11003139","title":"Human Complement Component C4c","description":"\u003cp\u003e\u003cstrong\u003eHuman Complement Component C4c\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eComplement C4c is a degradation product of C4b which is cleaved by C4b\/C3b inactivator to yield C4d and C4c. Complement C4c interacts with C1 and C2 to form C3 convertase of the classic activation pathway. Systemic lupus erythematosus (SLE) is often associated with congenital C4 deficiency. Reduced levels of components of the classic pathway (C1, C2, C4, C3) are common after such activation, e.g. in SLE, acute serum sickness and conditions associated with circulating immune complexes.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e\n\u003ch3\u003eActivity \u0026amp; assay information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHuman Virus Test:\u003c\/strong\u003e Plasma from each donor has been tested and found negative for HIV-1 \u0026amp; 2 antibodies, Hepatatis B surface antigen, and Hepatatis C antibodies.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"200 ug","offer_id":53038102774125,"sku":"pro-556-200UG","price":165.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038387462509,"sku":"pro-556-1MG","price":495.0,"currency_code":"USD","in_stock":true},{"title":"10 mg","offer_id":53038387495277,"sku":"pro-556-10MG","price":3850.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-complement-c4c-human-PRO-556.png?v=1782158240","url":"https:\/\/www.ebiohippo.com\/products\/human-complement-component-c4c-bhp11003139","provider":"BioHippo","version":"1.0","type":"link"}