{"product_id":"human-complement-factor-d-bhp11006058","title":"Human Complement Factor D","description":"\u003cp\u003e\u003cstrong\u003eHuman Complement Factor D\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCFD is an important component of the alternative pathway of complement activation. CFD cleaves and activates factor B when it binds C3b or a C3b-like protein such as C3 or CVF. CFD is a serine protease that exists as a mature protease, but it exhibits a highly restricted specificity and it appears to be substrate activated. CFD cleaves factor B bound to C3b leading to the release of the Ba fragment and leaving the Bb fragment bound to C3b. The C3b,Bb complex is called a C3 or C5 convertase because it converts these proteins to their active forms by cleaving off the small peptides C3a and C5a, respectively.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e\n\u003ch3\u003eActivity \u0026amp; assay information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHuman Virus Test:\u003c\/strong\u003e Plasma from each donor has been tested and found negative for antibody to HIV-1, HIV-2, HCV and HBSAG.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"1 ug","offer_id":53038181712237,"sku":"pro-2699-1UG","price":90.0,"currency_code":"USD","in_stock":true},{"title":"5 ug","offer_id":53038542520685,"sku":"pro-2699-5UG","price":220.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53038542553453,"sku":"pro-2699-50UG","price":1540.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cfd-human-PRO-2699.png?v=1782158392","url":"https:\/\/www.ebiohippo.com\/products\/human-complement-factor-d-bhp11006058","provider":"BioHippo","version":"1.0","type":"link"}