{"product_id":"human-double-strand-break-repair-protein-mre11a-mre11a-elisa-kit-bhe13703755","title":"Human Double-strand break repair protein MRE11A (MRE11A) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Double-strand break repair protein MRE11A (MRE11A) ELISA Kit has high sensitivity and excellent specificity for detection of Human MRE11A. No significant cross-reactivity or interference between Human MRE11A and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eMRE11A encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. MRE11A has a pseudogene on chromosome 3. Alternative splicing of MRE11A results in two transcript variants encoding different isoforms.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338635567469,"sku":"KTE61540-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338827555181,"sku":"KTE61540-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338827587949,"sku":"KTE61540-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338827620717,"sku":"KTE61540-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61540.png?v=1778954768","url":"https:\/\/www.ebiohippo.com\/products\/human-double-strand-break-repair-protein-mre11a-mre11a-elisa-kit-bhe13703755","provider":"BioHippo","version":"1.0","type":"link"}