{"product_id":"human-e3-ubiquitin-protein-ligase-trim21-trim21-elisa-kit-bhe12115277","title":"Human E3 Ubiquitin-protein Ligase Trim21, TRIM21 ELISA Kit","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eE3 Ubiquitin-protein Ligase Trim21 (TRIM21)\u003c\/strong\u003e is a molecular target commonly studied in epigenetics and nuclear signaling and immunology research. Immunoglobulins are antibody proteins central to humoral immunity and antigen recognition.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eUniProt\u003c\/strong\u003e: P19474\u003c\/p\u003e\u003ch2\u003eBiological role and pathway context\u003c\/h2\u003e\u003cp\u003eIn the literature, E3 Ubiquitin-protein Ligase Trim21 (TRIM21) is frequently examined in relation to innate and adaptive immune responses, cytokine signaling networks, and immune cell activation and trafficking. Depending on the model system, changes in abundance can be associated with shifts in signaling state, cellular composition, or tissue physiology.\u003c\/p\u003e\u003ch2\u003eExpression and regulation\u003c\/h2\u003e\u003cp\u003eExpression of E3 Ubiquitin-protein Ligase Trim21 (TRIM21) can vary across tissues and cell types and may change under conditions such as immune activation, stress responses, injury, infection, or metabolic perturbation. Reported regulation may involve transcriptional control as well as post-translational processes that influence stability, localization, processing, or secretion.\u003c\/p\u003e\u003ch2\u003eResearch and disease relevance\u003c\/h2\u003e\u003cp\u003eE3 Ubiquitin-protein Ligase Trim21 (TRIM21) has been reported as a useful readout in studies of physiological regulation and disease-associated processes. These observations make it relevant for hypothesis-driven research and biomarker exploration, while interpretation should remain grounded in the specific species, sample matrix, and study design.\u003c\/p\u003e\u003ch2\u003eInterpreting concentration measurements\u003c\/h2\u003e\u003cp\u003eMeasured levels of E3 Ubiquitin-protein Ligase Trim21 (TRIM21) can reflect multiple biological factors, including production rate, turnover, compartmental distribution, and sample composition. As a result, conclusions are often supported by considering broader pathway context and complementary readouts rather than relying on a single analyte alone.\u003c\/p\u003e\u003ch2\u003eNomenclature\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eE3 Ubiquitin-protein Ligase Trim21 (TRIM21)\u003c\/strong\u003e may also be referred to as \u003cstrong\u003e52 kDa ribonucleoprotein autoantigen Ro\/SS-A\u003c\/strong\u003e, \u003cstrong\u003e52 kDa Ro protein\u003c\/strong\u003e, and \u003cstrong\u003eE3 ubiquitin-protein ligase TRIM21\u003c\/strong\u003e in publications and databases. Nomenclature differences and species context can influence how results are compared across studies.\u003c\/p\u003e","brand":"Bioassay Technology Laboratory","offers":[{"title":"96T","offer_id":52952720736621,"sku":"E6796Hu-96T","price":458.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/E6796Hu.jpg?v=1769147605","url":"https:\/\/www.ebiohippo.com\/products\/human-e3-ubiquitin-protein-ligase-trim21-trim21-elisa-kit-bhe12115277","provider":"BioHippo","version":"1.0","type":"link"}