{"product_id":"human-endothelin-3-bhp11002573","title":"Human Endothelin-3","description":"\u003cp\u003e\u003cstrong\u003eHuman Endothelin-3\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eEDN3 interacts with endothelin receptor B, on the surface of cells. Throughout embryonic development, EDN3 takes part in neural crest cells that migrate from the developing spinal cord to specific regions in the embryo, where they give rise to many different types of cells. EDN3 and EDN3R are necessary for the formation of nerves in the large intestine (enteric nerves) and melanocytes (produce melanin). Mutations in the EDN3 gene is linked with Waardenburg syndrome, type IV that is characterized by changes in skin, hair, and eye coloring. Mutations in the EDN3 gene is linked with Hirschsprung disease that causes severe constipation or intestinal blockage.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e\n\u003ch3\u003eActivity \u0026amp; assay information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePeptide Content:\u003c\/strong\u003e 88%.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"1 mg","offer_id":53038085701997,"sku":"hor-309-1MG","price":300.0,"currency_code":"USD","in_stock":true},{"title":"5 mg","offer_id":53038352204141,"sku":"hor-309-5MG","price":1320.0,"currency_code":"USD","in_stock":true},{"title":"10 mg","offer_id":53038352236909,"sku":"hor-309-10MG","price":2285.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-edn3-human-HOR-309.png?v=1782158202","url":"https:\/\/www.ebiohippo.com\/products\/human-endothelin-3-bhp11002573","provider":"BioHippo","version":"1.0","type":"link"}