{"product_id":"human-exportin-1-xpo1-elisa-kit-bhe13702232","title":"Human Exportin-1 (XPO1) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Exportin-1 (XPO1) ELISA Kit has high sensitivity and excellent specificity for detection of Human XPO1. No significant cross-reactivity or interference between Human XPO1 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eExportin-1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2.\u003c\/p\u003e\u003cp\u003eThis protein also regulates NFAT and AP-1.The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Involved in U3 snoRNA transport from Cajal bodies to nucleoli. Binds to late precursor U3 snoRNA bearing a TMG cap. Several viruses, among them HIV-1, HTLV-1 and influenza A use it to export their unspliced or incompletely spliced RNAs out of the nucleus.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338582024557,"sku":"KTE60012-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338666271085,"sku":"KTE60012-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338666303853,"sku":"KTE60012-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338666336621,"sku":"KTE60012-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60012.png?v=1778954614","url":"https:\/\/www.ebiohippo.com\/products\/human-exportin-1-xpo1-elisa-kit-bhe13702232","provider":"BioHippo","version":"1.0","type":"link"}