{"product_id":"human-exportin-5-xpo5-elisa-kit-bhe13702231","title":"Human Exportin-5 (XPO5) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Exportin-5 (XPO5) ELISA Kit has high sensitivity and excellent specificity for detection of Human XPO5. No significant cross-reactivity or interference between Human XPO5 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eExportin-5 belongs to a large family of karyopherins that mediate the transport of proteins and other cargo between the nuclear and cytoplasmic compartments. The deduced 1,205-amino acid protein has a calculated molecular mass of about 136 kD. XPO5 and XPO1 share 25% amino acid identity.\u003c\/p\u003e\u003cp\u003eNorthern blot analysis detected transcripts of about 3.6 and 5.0 kb in all tissues examined.XPO5 bound the nucleoporins NUP214 and NUP153 in a RAN-GTP-independent manner and bound a cargo protein, ILF3, in a RAN-GTP-dependent manner. XPO5 bound ILF3 at its double-stranded RNA-binding domain (dsRBD) and also bound the dsRBDs of other proteins. XPO5 directly interacted with VA1 RNA in a RAN-GTP-dependent manner.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338582155629,"sku":"KTE60011-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338669711725,"sku":"KTE60011-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338669744493,"sku":"KTE60011-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338669777261,"sku":"KTE60011-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/human-exportin-5-xpo5-elisa-kit-bhe13702231","provider":"BioHippo","version":"1.0","type":"link"}