{"product_id":"human-glia-derived-nexin-serpine2-elisa-kit-bhe13702909","title":"Human Glia-derived nexin (SERPINE2) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Glia-derived nexin (SERPINE2) ELISA Kit has high sensitivity and excellent specificity for detection of Human SERPINE2. No significant cross-reactivity or interference between Human SERPINE2 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eProtease nexin I is a 44-kD thrombin and urokinase inhibitor released by human foreskin fibroblasts. PN-I shares several features with antithrombin III , an abundant plasma thrombin inhibitor. Both PN-I and AT-III have high affinities for heparin, and heparin accelerates their rate of thrombin inhibition. In addition, the published sequence of 28 amino acids at the N-terminus of PN-I is identical to the N-terminal amino acid sequence of a glial-derived neurite promoting factor. Two forms, designated alpha and beta, were identified. These differed only by the insertion of 3 nucleotides into the coding sequence, and apparently arose by utilization of an alternative splice acceptor site in the PN1 gene. In the resulting proteins, alpha-PN-I contains an arginine residue at position 310, whereas beta-PN-I contains threonine-lysine residues.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338607845741,"sku":"KTE60693-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338745667949,"sku":"KTE60693-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338745700717,"sku":"KTE60693-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338745733485,"sku":"KTE60693-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60693.png?v=1778954685","url":"https:\/\/www.ebiohippo.com\/products\/human-glia-derived-nexin-serpine2-elisa-kit-bhe13702909","provider":"BioHippo","version":"1.0","type":"link"}