{"product_id":"human-glutamate-cysteine-ligase-regulatory-subunit-gclm-elisa-kit-bhe12106702","title":"Human Glutamate--cysteine Ligase Regulatory Subunit, GCLM ELISA Kit","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eGlutamate--cysteine Ligase Regulatory Subunit (GCLM)\u003c\/strong\u003e is a molecular target commonly studied in neuroscience research. Immunoglobulins are antibody proteins central to humoral immunity and antigen recognition.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eUniProt\u003c\/strong\u003e: P48507\u003c\/p\u003e\u003ch2\u003eBiological role and pathway context\u003c\/h2\u003e\u003cp\u003eIn the literature, Glutamate--cysteine Ligase Regulatory Subunit (GCLM) is frequently examined in relation to neuronal signaling and synaptic function, neuroinflammation and glial responses, and neurodegeneration models. Depending on the model system, changes in abundance can be associated with shifts in signaling state, cellular composition, or tissue physiology.\u003c\/p\u003e\u003ch2\u003eExpression and regulation\u003c\/h2\u003e\u003cp\u003eExpression of Glutamate--cysteine Ligase Regulatory Subunit (GCLM) can vary across tissues and cell types and may change under conditions such as immune activation, stress responses, injury, infection, or metabolic perturbation. Reported regulation may involve transcriptional control as well as post-translational processes that influence stability, localization, processing, or secretion.\u003c\/p\u003e\u003ch2\u003eResearch and disease relevance\u003c\/h2\u003e\u003cp\u003eGlutamate--cysteine Ligase Regulatory Subunit (GCLM) has been reported as a useful readout in studies of physiological regulation and disease-associated processes. These observations make it relevant for hypothesis-driven research and biomarker exploration, while interpretation should remain grounded in the specific species, sample matrix, and study design.\u003c\/p\u003e\u003ch2\u003eInterpreting concentration measurements\u003c\/h2\u003e\u003cp\u003eMeasured levels of Glutamate--cysteine Ligase Regulatory Subunit (GCLM) can reflect multiple biological factors, including production rate, turnover, compartmental distribution, and sample composition. As a result, conclusions are often supported by considering broader pathway context and complementary readouts rather than relying on a single analyte alone.\u003c\/p\u003e\u003ch2\u003eNomenclature\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eGlutamate--cysteine Ligase Regulatory Subunit (GCLM)\u003c\/strong\u003e may also be referred to as \u003cstrong\u003eGamma-ECS regulatory subunit\u003c\/strong\u003e, \u003cstrong\u003eGamma-glutamylcysteine synthetase regulatory subunit\u003c\/strong\u003e, and \u003cstrong\u003eGCLM\u003c\/strong\u003e in publications and databases. Nomenclature differences and species context can influence how results are compared across studies.\u003c\/p\u003e","brand":"Bioassay Technology Laboratory","offers":[{"title":"96T","offer_id":52952571019629,"sku":"E5339Hu-96T","price":458.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/E5339Hu.jpg?v=1769146714","url":"https:\/\/www.ebiohippo.com\/products\/human-glutamate-cysteine-ligase-regulatory-subunit-gclm-elisa-kit-bhe12106702","provider":"BioHippo","version":"1.0","type":"link"}