{"product_id":"human-glutaminyl-peptide-cyclotransferase-qpct-elisa-kit-bhe13703221","title":"Human Glutaminyl-peptide cyclotransferase (QPCT) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Glutaminyl-peptide cyclotransferase (QPCT) ELISA Kit has high sensitivity and excellent specificity for detection of Human QPCT. No significant cross-reactivity or interference between Human QPCT and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eQPCT encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase.\u003c\/p\u003e\u003cp\u003eThe deduced 361-amino acid protein has a calculated molecular mass of about 41 kD. It contains an N-terminal signal peptide region, several glycosylation and phosphorylation sites, and 2 cysteine residues conserved between the bovine and human enzymes. QPCT shares 86% overall sequence identity with the bovine homolog.Glutaminyl cyclase expression was upregulated in the cortices of individuals with Alzheimer disease and correlated with the appearance of pE-modified amyloid beta.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338618134893,"sku":"KTE61005-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338774438253,"sku":"KTE61005-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338774471021,"sku":"KTE61005-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338774503789,"sku":"KTE61005-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61005.png?v=1778954716","url":"https:\/\/www.ebiohippo.com\/products\/human-glutaminyl-peptide-cyclotransferase-qpct-elisa-kit-bhe13703221","provider":"BioHippo","version":"1.0","type":"link"}