{"product_id":"human-lactoferrin-bhp10506050","title":"Human lactoferrin","description":"\u003ch2\u003eOverview\u003c\/h2\u003e \u003cp\u003eNative human lactoferrin (LTF) is purified from human milk and supplied as a research reagent. It is commonly used as a reference material in biochemical and analytical workflows, and to support interpretation when naturally occurring proteoforms (for example, glycosylation or other post‑translational modifications) may matter.\u003c\/p\u003e \u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e \u003cul\u003e \u003cli\u003e\n\u003cstrong\u003eNative-source preparation:\u003c\/strong\u003e Purified from a biological source, which can be useful when studying naturally occurring proteoforms and complex formation.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eMolecular form:\u003c\/strong\u003e Full length protein.\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eClassification:\u003c\/strong\u003e Storage Protein\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;95%(SDS-PAGE) (as reported).\u003c\/li\u003e \u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e Liquid\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThese elements help determine how the reagent behaves in binding, stability, or quantitative measurements, and how closely it reflects biology in the chosen model system.\u003c\/p\u003e \u003ch2\u003eBiological background\u003c\/h2\u003e \u003cp\u003eLactoferrin is an iron-binding glycoprotein abundant in mucosal secretions and neutrophil granules, often studied for roles in iron sequestration, antimicrobial defense, and immunomodulation. Its iron-binding state and glycosylation can influence interactions with cells and microbes.\u003c\/p\u003e\u003cp\u003eLactoferrin is a glycoprotein present in most human mucosal secretions, including human milk. Lactoferrin is bacteriostatic in low iron media and, in some settings, bactericidal.\u003c\/p\u003e \u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eMucosal immunity and microbiome research examining nutrient sequestration and antimicrobial protein networks.\u003c\/li\u003e \u003cli\u003eInflammation biology focusing on neutrophil-driven secreted factors and their downstream signaling effects.\u003c\/li\u003e \u003cli\u003eBiophysical studies of iron-binding proteins and how iron occupancy alters stability and ligand interactions.\u003c\/li\u003e \u003c\/ul\u003e \u003ch2\u003eCommon research applications\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eReference reagent in immunoassays or binding studies involving iron-binding glycoproteins.\u003c\/li\u003e \u003cli\u003eHost–microbe interaction studies where iron availability shapes growth and immune responses.\u003c\/li\u003e \u003cli\u003eComparative studies of apo\/holo forms and glycoform-dependent binding behaviors.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eUse changes in abundance, binding, or activity readouts as context-dependent signals. In many systems, differences may reflect regulation, compartment shifts, complex formation, or sample-matrix effects rather than a single direct mechanism.\u003c\/p\u003e \u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e \u003cul\u003e \u003cli\u003eIron saturation (apo vs holo) can change binding and functional interpretations; document iron state when relevant.\u003c\/li\u003e \u003cli\u003eNative lactoferrin may show glycoform heterogeneity dependent on source; this can influence receptor interactions.\u003c\/li\u003e \u003cli\u003eEffects observed in complex matrices can reflect indirect immune signaling; consider orthogonal readouts.\u003c\/li\u003e \u003c\/ul\u003e \u003c!-- Sources (internal): - UniProt: https:\/\/www.uniprot.org\/uniprotkb?query=lactoferrin LTF - NCBI Gene: https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=lactoferrin LTF - PubMed: https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=lactoferrin LTF%20review --\u003e","brand":"CUSABIO TECHNOLOGY LLC","offers":[{"title":"10 mg","offer_id":53052972695917,"sku":"CSB-NP008701h-10MG","price":3605.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53052972728685,"sku":"CSB-NP008701h-1MG","price":450.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/CSB-NP008701h-SDS.jpg?v=1772166488","url":"https:\/\/www.ebiohippo.com\/products\/human-lactoferrin-bhp10506050","provider":"BioHippo","version":"1.0","type":"link"}