{"product_id":"human-lipolysis-stimulated-lipoprotein-receptor-lsr-elisa-kit-bhe13703990","title":"Human Lipolysis-stimulated lipoprotein receptor (LSR) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Lipolysis-stimulated lipoprotein receptor (LSR) ELISA Kit has high sensitivity and excellent specificity for detection of Human LSR. No significant cross-reactivity or interference between Human LSR and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eLSR is a multimeric protein complex in the liver that undergoes conformational changes upon binding of free fatty acids, thereby revealing a binding site (s) that recognizes both apoB and apoE. Complete inactivation of the LSR gene is embryonic lethal in mice.LSR cooperates with the LDL receptor in the final hepatic processing of apoB-containing lipoproteins and represents a novel therapeutic target for the treatment of hyperlipidemia associated with obesity and atherosclerosis. The lipolysis-stimulated receptor (LSR) is a lipoprotein receptor primarily expressed in the liver and activated by free fatty acids. Antibodies inhibiting LSR functions showed that the receptor is a heterotrimer or tetramer consisting of 68-kDa (alpha) and 56-kDa (beta) subunits associated through disulfide bridges.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338642940269,"sku":"KTE61775-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338850230637,"sku":"KTE61775-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338850263405,"sku":"KTE61775-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338850296173,"sku":"KTE61775-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61775.png?v=1778954790","url":"https:\/\/www.ebiohippo.com\/products\/human-lipolysis-stimulated-lipoprotein-receptor-lsr-elisa-kit-bhe13703990","provider":"BioHippo","version":"1.0","type":"link"}