{"product_id":"human-low-density-lipoprotein-receptor-related-protein-lrp-6-elisa-kit-bhe13703996","title":"Human Low-density lipoprotein-receptor-related protein (LRP-6) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Low-density lipoprotein-receptor-related protein (LRP-6) ELISA Kit has high sensitivity and excellent specificity for detection of Human LRP6. No significant cross-reactivity or interference between Human LRP6 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe LRP6 is a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt\/beta-catenin signaling cascade. Through its interaction with the Wnt\/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338643431789,"sku":"KTE61781-48T","price":359.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338850623853,"sku":"KTE61781-96T","price":619.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338850656621,"sku":"KTE61781-96TX5","price":2809.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338850689389,"sku":"KTE61781-96TX50","price":26209.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61781.png?v=1778954792","url":"https:\/\/www.ebiohippo.com\/products\/human-low-density-lipoprotein-receptor-related-protein-lrp-6-elisa-kit-bhe13703996","provider":"BioHippo","version":"1.0","type":"link"}