{"product_id":"human-macoilin-tmem57-elisa-kit-bhe13702493","title":"Human Macoilin (TMEM57) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Macoilin (TMEM57) ELISA Kit has high sensitivity and excellent specificity for detection of Human TMEM57. No significant cross-reactivity or interference between Human TMEM57 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eTMEM57 has 5 domains, including an N-terminal LAG1 domain and a central ERM-myosin filament domain. The LAG1 domain contains 3 putative transmembrane domains. In situ hybridization of mouse embryos showed that Tmem57 was brain specific.\u003c\/p\u003e\u003cp\u003eIt was primarily associated with postmigratory neurons and less so with neural proliferating cells, and Tmem57 expression was progressively downregulated during brain maturation. Fluorescence-tagged Tmem57 outlined the nuclear membrane when expressed in nonneuronal cells. In primary hippocampal neurons, Tmem57 was found in neurites and their terminals, and it partially colocalized with synapsin-1 (SYN1), a presynaptic marker.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338593853805,"sku":"KTE60275-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338702643565,"sku":"KTE60275-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338702676333,"sku":"KTE60275-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338702709101,"sku":"KTE60275-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60275.png?v=1778954642","url":"https:\/\/www.ebiohippo.com\/products\/human-macoilin-tmem57-elisa-kit-bhe13702493","provider":"BioHippo","version":"1.0","type":"link"}