{"product_id":"human-malate-dehydrogenase-1-mdh1-elisa-kit-bhe13703896","title":"Human Malate Dehydrogenase 1 (MDH1) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Malate Dehydrogenase 1 (MDH1) ELISA Kit has high sensitivity and excellent specificity for detection of Human MDH1. No significant cross-reactivity or interference between Human MDH1 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eMDH1 encodes an enzyme that catalyzes the NAD\/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. MDH1 encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338640777581,"sku":"KTE61681-48T","price":359.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338841088365,"sku":"KTE61681-96T","price":619.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338841121133,"sku":"KTE61681-96TX5","price":2809.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338841153901,"sku":"KTE61681-96TX50","price":26209.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61681.png?v=1778954783","url":"https:\/\/www.ebiohippo.com\/products\/human-malate-dehydrogenase-1-mdh1-elisa-kit-bhe13703896","provider":"BioHippo","version":"1.0","type":"link"}