{"product_id":"human-mediator-of-rna-polymerase-ii-transcription-subunit-14-med14-elisa-kit-bhe13703882","title":"Human Mediator of RNA polymerase II transcription subunit 14 (MED14) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Mediator of RNA polymerase II transcription subunit 14 (MED14) ELISA Kit has high sensitivity and excellent specificity for detection of Human MED14. No significant cross-reactivity or interference between Human MED14 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. Mediator of RNA polymerase II transcription subunit 14 encoded by MED14 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Mediator of RNA polymerase II transcription subunit 14 contains a bipartite nuclear localization signal. MED14 is known to escape chromosome X-inactivation.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338639532397,"sku":"KTE61667-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338839908717,"sku":"KTE61667-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338839941485,"sku":"KTE61667-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338839974253,"sku":"KTE61667-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61667.png?v=1778954778","url":"https:\/\/www.ebiohippo.com\/products\/human-mediator-of-rna-polymerase-ii-transcription-subunit-14-med14-elisa-kit-bhe13703882","provider":"BioHippo","version":"1.0","type":"link"}