{"product_id":"human-mitochondrial-import-receptor-subunit-tom70-tomm70a-elisa-kit-bhe13702378","title":"Human Mitochondrial import receptor subunit TOM70 (TOMM70A) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Mitochondrial import receptor subunit TOM70 (TOMM70A) ELISA Kit has high sensitivity and excellent specificity for detection of Human TOMM70A. No significant cross-reactivity or interference between Human TOMM70A and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe translocase of outer mitochondrial membrane (TOM) complex is a multisubunit complex involved in the recognition, unfolding, and translocation of preproteins into the mitochondria.TOMM70A is 29% identical to the mitochondrial precursor protein import receptor of Neurospora crassa. RT-PCR analysis detected ubiquitous expression of KIAA0719, with relatively weak expression in pancreas, testis, and spleen.the cytosolic chaperones HSP90 and HSP70 dock onto a specialized tetratricopeptide domain in the import receptor TOMM70 at the outer mitochondrial membrane. This interaction served to deliver a set of preproteins to the receptor for subsequent membrane translocation dependent on the HSP90 ATPase. Disruption of the chaperone\/TOMM70 recognition inhibited the import of these preproteins into mitochondria.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338589397357,"sku":"KTE60159-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338690683245,"sku":"KTE60159-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338690716013,"sku":"KTE60159-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338690748781,"sku":"KTE60159-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60159.png?v=1778954632","url":"https:\/\/www.ebiohippo.com\/products\/human-mitochondrial-import-receptor-subunit-tom70-tomm70a-elisa-kit-bhe13702378","provider":"BioHippo","version":"1.0","type":"link"}