{"product_id":"human-mms19-nucleotide-excision-repair-protein-homolog-mms19-elisa-kit-bhe13703797","title":"Human MMS19 nucleotide excision repair protein homolog (MMS19) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman MMS19 nucleotide excision repair protein homolog (MMS19) ELISA Kit has high sensitivity and excellent specificity for detection of Human MMS19. No significant cross-reactivity or interference between Human MMS19 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eMMS19 (MMS19 Homolog, Cytosolic Iron-Sulfur Assembly Component) is a Protein Coding gene. Among its related pathways are Metabolism and Cytosolic iron-sulfur cluster assembly. GO annotations related to this gene include binding and protein binding, bridging. Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2\/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2\/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338635698541,"sku":"KTE61582-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338831192429,"sku":"KTE61582-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338831225197,"sku":"KTE61582-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338831257965,"sku":"KTE61582-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61582.png?v=1778954774","url":"https:\/\/www.ebiohippo.com\/products\/human-mms19-nucleotide-excision-repair-protein-homolog-mms19-elisa-kit-bhe13703797","provider":"BioHippo","version":"1.0","type":"link"}