{"product_id":"human-mucin-1-ca15-3-bhp11006139","title":"Human Mucin-1 (CA15-3)","description":"\u003cp\u003e\u003cstrong\u003eHuman Mucin-1 (CA15-3)\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eHuman Mucin-1 (CA15-3), aka MUC1, is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. This protein has alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit roles in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Mucins line the apical surface of epithelial cells in the stomach, lungs, intestines, eyes and other tissues. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Overexpression of CA15-3 is often associated with colon, breast, ovarian, lung and pancreatic cancers.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e\n\u003ch3\u003eActivity \u0026amp; assay information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHuman Virus Test:\u003c\/strong\u003e Tissue sample tested and found negative for HIV-1 \u0026amp; 2 antibodies, HBsAg, and Hepatitis-C antibodies, Syphilis and HIV\/HBV\/HCV NAT.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"10 KU","offer_id":53038184071533,"sku":"pro-2747-10KU","price":1500.0,"currency_code":"USD","in_stock":true},{"title":"25 KU","offer_id":53038551466349,"sku":"pro-2747-25KU","price":2800.0,"currency_code":"USD","in_stock":true},{"title":"50 KU","offer_id":53038551499117,"sku":"pro-2747-50KU","price":4500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ca15-3-muc1-human-PRO-2747.png?v=1782158396","url":"https:\/\/www.ebiohippo.com\/products\/human-mucin-1-ca15-3-bhp11006139","provider":"BioHippo","version":"1.0","type":"link"}