{"product_id":"human-myristoylated-alanine-rich-c-kinase-substrate-marcks-elisa-kit-bhe13703937","title":"Human Myristoylated alanine-rich C-kinase substrate (MARCKS) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Myristoylated alanine-rich C-kinase substrate (MARCKS) ELISA Kit has high sensitivity and excellent specificity for detection of Human MARCKS. No significant cross-reactivity or interference between Human MARCKS and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eMARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. MARCKS is a filamentous actin crosslinking protein, with activity that is inhibited by PKC-mediated phosphorylation and by binding to calcium-calmodulin. MARCKS may be a regulated crossbridge between actin and the plasma membrane, and modulation of the actin crosslinking activity of the MARCKS protein by calmodulin and phosphorylation represents a potential convergence of the calcium-calmodulin and protein kinase C signal transduction pathways in the regulation of the actin cytoskeleton.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338640974189,"sku":"KTE61722-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338846003565,"sku":"KTE61722-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338846036333,"sku":"KTE61722-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338846069101,"sku":"KTE61722-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61722.png?v=1778954784","url":"https:\/\/www.ebiohippo.com\/products\/human-myristoylated-alanine-rich-c-kinase-substrate-marcks-elisa-kit-bhe13703937","provider":"BioHippo","version":"1.0","type":"link"}