{"product_id":"human-n-acetylglucosamine-1-phosphodiester-alpha-n-acetylglucosaminidase-nagpa-elisa-kit-bhe13703601","title":"Human N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA) ELISA Kit has high sensitivity and excellent specificity for detection of Human NAGPA. No significant cross-reactivity or interference between Human NAGPA and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network. NAGPA encodes the enzyme that catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as 'uncovering enzyme' or UCE, this enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues from GlcNAc-alpha-P-mannose moieties and thereby produces the recognition marker. The encoded preproprotein is proteolytically processed by furin to generate the mature enzyme, a homotetramer of two disulfide-linked homodimers. Mutations in NAGPA are associated with developmental stuttering in human patients\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338629734765,"sku":"KTE61386-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338812219757,"sku":"KTE61386-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338812252525,"sku":"KTE61386-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338812285293,"sku":"KTE61386-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61386.png?v=1778954755","url":"https:\/\/www.ebiohippo.com\/products\/human-n-acetylglucosamine-1-phosphodiester-alpha-n-acetylglucosaminidase-nagpa-elisa-kit-bhe13703601","provider":"BioHippo","version":"1.0","type":"link"}