{"product_id":"human-nad-dependent-deacetylase-sirtuin-6-sirt6-sir2l6-elisa-kit-bhe13702865","title":"Human NAD-dependent deacetylase sirtuin-6 (SIRT6\/SIR2L6) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman NAD-dependent deacetylase sirtuin-6 (SIRT6\/SIR2L6) ELISA Kit has high sensitivity and excellent specificity for detection of Human SIRT6. No significant cross-reactivity or interference between Human SIRT6 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eSIRT6 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.Sirtuins can be divided into 4 main classes in eukaryotes based on amino acid sequence motifs, with yeast Sir2 belonging to class Ia. The deduced 355-amino acid SIRT6 protein is a class IV sirtuin, a class not present in prokaryotes.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338606207341,"sku":"KTE60649-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338739278189,"sku":"KTE60649-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338739310957,"sku":"KTE60649-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338739343725,"sku":"KTE60649-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60649.png?v=1778954679","url":"https:\/\/www.ebiohippo.com\/products\/human-nad-dependent-deacetylase-sirtuin-6-sirt6-sir2l6-elisa-kit-bhe13702865","provider":"BioHippo","version":"1.0","type":"link"}