{"product_id":"human-nedd8-activating-enzyme-e1-regulatory-subunit-nae1-elisa-kit-bhe13703606","title":"Human NEDD8-activating enzyme E1 regulatory subunit (NAE1) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman NEDD8-activating enzyme E1 regulatory subunit (NAE1) ELISA Kit has high sensitivity and excellent specificity for detection of Human NAE1. No significant cross-reactivity or interference between Human NAE1 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eNEDD8-activating enzyme E1 regulatory subunit encoded by NAE1 binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S\/M checkpoint. Three transcript variants encoding different isoforms have been found for NAE1.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338630619501,"sku":"KTE61391-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338812514669,"sku":"KTE61391-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338812547437,"sku":"KTE61391-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338812580205,"sku":"KTE61391-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61391.png?v=1778954756","url":"https:\/\/www.ebiohippo.com\/products\/human-nedd8-activating-enzyme-e1-regulatory-subunit-nae1-elisa-kit-bhe13703606","provider":"BioHippo","version":"1.0","type":"link"}