{"product_id":"human-nuclear-receptor-coactivator-2-ncoa2-elisa-kit-bhe13703559","title":"Human Nuclear receptor coactivator 2 (NCOA2) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Nuclear receptor coactivator 2 (NCOA2) ELISA Kit has high sensitivity and excellent specificity for detection of Human NCOA2. No significant cross-reactivity or interference between Human NCOA2 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eNuclear receptor coactivator 2 encoded by NCOA2 functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. Nuclear receptor coactivator 2 acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. NCOA2 has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338628653421,"sku":"KTE61344-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338808090989,"sku":"KTE61344-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338808123757,"sku":"KTE61344-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338808156525,"sku":"KTE61344-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61344.png?v=1778954748","url":"https:\/\/www.ebiohippo.com\/products\/human-nuclear-receptor-coactivator-2-ncoa2-elisa-kit-bhe13703559","provider":"BioHippo","version":"1.0","type":"link"}