{"product_id":"human-p-selectin-selp-elisa-kit-bhe13703307","title":"Human P-Selectin (SELP) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman P-Selectin (SELP) ELISA Kit has high sensitivity and excellent specificity for detection of Human SELP. No significant cross-reactivity or interference between Human SELP and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eP-selectin is the largest of the known selectins at 140kDa. It contains nine consensus repeats (CR) and extends approximately 40 nm from the endothelial surface. P-selectin is expressed in a-granules of activated platelets and granules of endothelial cells. Within minutes of stimulation of the endothelial cells by inflammatory mediators such as histamine, thrombin, or phorbol esters, P-selectin is surface-expressed. Expression of P-selectin also occurs from the surgical trauma endured during preparation of the tissues for intravital microscopy. The expression is short-lived, reaching its peak after only ten minutes. Additional synthesis of P-selectin is brought about within two hours by cytokines such as interleukin-1 (IL-1) or tumor necrosis factor a (TNF-a).\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338620133741,"sku":"KTE61091-48T","price":399.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338784465261,"sku":"KTE61091-96T","price":739.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338784498029,"sku":"KTE61091-96TX5","price":3339.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338784530797,"sku":"KTE61091-96TX50","price":29639.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61091.png?v=1778954722","url":"https:\/\/www.ebiohippo.com\/products\/human-p-selectin-selp-elisa-kit-bhe13703307","provider":"BioHippo","version":"1.0","type":"link"}