{"product_id":"human-parathyroid-pormone-1-receptor-pth1r-elisa-kit-bhe13703281","title":"Human Parathyroid Pormone 1 Receptor (PTH1R) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Parathyroid Pormone 1 Receptor (PTH1R) ELISA Kit has high sensitivity and excellent specificity for detection of Human PTH1R. No significant cross-reactivity or interference between Human PTH1R and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eParathyroid hormone receptor 1 functions as a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH).This \"classical\" PTH receptor is expressed in high levels in bone and kidney and regulates calcium ion homeostasis through activation of adenylate cyclase and phospholipase C. In bone, it is expressed on the surface of osteoblasts. When the receptor is activated, these cells in turn stimulate osteoclasts to ultimately increase the resorption rate.It is a member of the secretin family of G protein-coupled receptors. The activity of this receptor is mediated by Gs G proteins which activate adenylyl cyclase. Besides, they also activate phosphatidylinositol-calcium second messenger system.Expressed in most tissues. Most abundant in kidney, bone and liver.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338619576685,"sku":"KTE61065-48T","price":359.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338780500333,"sku":"KTE61065-96T","price":619.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338780533101,"sku":"KTE61065-96TX5","price":2809.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338780565869,"sku":"KTE61065-96TX50","price":26209.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61065.png?v=1778954721","url":"https:\/\/www.ebiohippo.com\/products\/human-parathyroid-pormone-1-receptor-pth1r-elisa-kit-bhe13703281","provider":"BioHippo","version":"1.0","type":"link"}