{"product_id":"human-phenylethylamine-n-methyltransferase-pnmt-elisa-kit-bhe12115274","title":"Human Phenylethylamine N-methyltransferase, PNMT ELISA Kit","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003ePhenylethylamine N-methyltransferase (PNMT)\u003c\/strong\u003e is a molecular target commonly studied in neuroscience, cardiovascular, and cancer research. This molecule is commonly investigated as part of broader signaling, regulatory, or homeostatic networks.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eUniProt\u003c\/strong\u003e: P11086\u003c\/p\u003e\u003ch2\u003eBiological role and pathway context\u003c\/h2\u003e\u003cp\u003eIn the literature, Phenylethylamine N-methyltransferase (PNMT) is frequently examined in relation to neuronal signaling and synaptic function, neuroinflammation and glial responses, and neurodegeneration models. Depending on the model system, changes in abundance can be associated with shifts in signaling state, cellular composition, or tissue physiology.\u003c\/p\u003e\u003ch2\u003eExpression and regulation\u003c\/h2\u003e\u003cp\u003eExpression of Phenylethylamine N-methyltransferase (PNMT) can vary across tissues and cell types and may change under conditions such as immune activation, stress responses, injury, infection, or metabolic perturbation. Reported regulation may involve transcriptional control as well as post-translational processes that influence stability, localization, processing, or secretion.\u003c\/p\u003e\u003ch2\u003eResearch and disease relevance\u003c\/h2\u003e\u003cp\u003ePhenylethylamine N-methyltransferase (PNMT) has been reported as a useful readout in studies of physiological regulation and disease-associated processes. These observations make it relevant for hypothesis-driven research and biomarker exploration, while interpretation should remain grounded in the specific species, sample matrix, and study design.\u003c\/p\u003e\u003ch2\u003eInterpreting concentration measurements\u003c\/h2\u003e\u003cp\u003eMeasured levels of Phenylethylamine N-methyltransferase (PNMT) can reflect multiple biological factors, including production rate, turnover, compartmental distribution, and sample composition. As a result, conclusions are often supported by considering broader pathway context and complementary readouts rather than relying on a single analyte alone.\u003c\/p\u003e\u003ch2\u003eNomenclature\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003ePhenylethylamine N-methyltransferase (PNMT)\u003c\/strong\u003e may also be referred to as \u003cstrong\u003eNoradrenaline N-methyltransferase\u003c\/strong\u003e, \u003cstrong\u003ePENT\u003c\/strong\u003e, and \u003cstrong\u003ePhenylethanolamine N-methyltransferase\u003c\/strong\u003e in publications and databases. Nomenclature differences and species context can influence how results are compared across studies.\u003c\/p\u003e","brand":"Bioassay Technology Laboratory","offers":[{"title":"96T","offer_id":52952720605549,"sku":"E6788Hu-96T","price":458.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/E6788Hu.jpg?v=1769147604","url":"https:\/\/www.ebiohippo.com\/products\/human-phenylethylamine-n-methyltransferase-pnmt-elisa-kit-bhe12115274","provider":"BioHippo","version":"1.0","type":"link"}