{"product_id":"human-pre-mrna-processing-factor-6-prpf6-elisa-kit-bhe13703334","title":"Human Pre-mRNA-processing factor 6 (PRPF6) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Pre-mRNA-processing factor 6 (PRPF6) ELISA Kit has high sensitivity and excellent specificity for detection of Human PRPF6. No significant cross-reactivity or interference between Human PRPF6 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003ePRP6 appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4\/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing. Predicted amino acid sequence of the protein is similar to those of yeast splicing factors, Prp1p\/Zer1p of Schizosaccharomyces pombe and Prp6p of Saccharomyces cerevisiae. Among these proteins, tetratrico peptide repeat (TPR) motif, which mediates protein-protein interactions, is conserved, whereas leucine zipper motif is found only in the 100-kDa protein. Indirect immunofluorescent staining showed that the 100-kDa protein localized in the nucleus in HeLa cells.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338621149549,"sku":"KTE61118-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338785775981,"sku":"KTE61118-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338785808749,"sku":"KTE61118-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338785841517,"sku":"KTE61118-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61118.png?v=1778954725","url":"https:\/\/www.ebiohippo.com\/products\/human-pre-mrna-processing-factor-6-prpf6-elisa-kit-bhe13703334","provider":"BioHippo","version":"1.0","type":"link"}