{"product_id":"human-protein-l-isoaspartate-pcmt1-elisa-kit-bhe13703508","title":"Human Protein-L-isoaspartate (PCMT1) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Protein-L-isoaspartate (PCMT1) ELISA Kit has high sensitivity and excellent specificity for detection of Human PCMT1. No significant cross-reactivity or interference between Human PCMT1 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThree classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues.\u003c\/p\u003e\u003cp\u003eThese methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338626883949,"sku":"KTE61292-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338803110253,"sku":"KTE61292-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338803143021,"sku":"KTE61292-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338803175789,"sku":"KTE61292-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61292.png?v=1778954742","url":"https:\/\/www.ebiohippo.com\/products\/human-protein-l-isoaspartate-pcmt1-elisa-kit-bhe13703508","provider":"BioHippo","version":"1.0","type":"link"}