{"product_id":"human-protein-mrvi1-mrvi1-elisa-kit-bhe13703739","title":"Human Protein MRVI1 (MRVI1) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Protein MRVI1 (MRVI1) ELISA Kit has high sensitivity and excellent specificity for detection of Human MRVI1. No significant cross-reactivity or interference between Human MRVI1 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eMRVI1 is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). Protein MRVI1, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and\/or differentiation, and thus MRVI1 may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for MRVI1, and alternative translation start sites, including a non-AUG (CUG) start site, are used.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338634813805,"sku":"KTE61524-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338825687405,"sku":"KTE61524-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338825720173,"sku":"KTE61524-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338825752941,"sku":"KTE61524-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61524.png?v=1778954771","url":"https:\/\/www.ebiohippo.com\/products\/human-protein-mrvi1-mrvi1-elisa-kit-bhe13703739","provider":"BioHippo","version":"1.0","type":"link"}