{"product_id":"human-protein-phosphatase-slingshot-homolog-1-ssh1-elisa-kit-bhe13702583","title":"Human Protein phosphatase Slingshot homolog 1 (SSH1) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Protein phosphatase Slingshot homolog 1 (SSH1) ELISA Kit has high sensitivity and excellent specificity for detection of Human SSH1. No significant cross-reactivity or interference between Human SSH1 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe ADF (actin-depolymerizing factor)\/cofilin family is composed of stimulus-responsive mediators of actin dynamics. ADF\/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1). The SSH family appears to play a role in actin dynamics by reactivating ADF\/cofilin proteins in vivo. Transcript analysis suggested that at least 6 polypeptides would be produced from these genes. SSH1 encodes 3 isoforms, SSH1L (1,049 amino acids), SSH1S (692 amino acids), and SSH1B (148 amino acids), and SSH2 encodes 2 isoforms, SSH2 (449 amino acids) and SSH2B (195 amino acids). The SSH3 protein has 471 amino acids. Besides the catalytic domain, 2 other domains are conserved between Drosophila ssh and the human SSHs and are unique to the SSH family.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338596049261,"sku":"KTE60366-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338711949677,"sku":"KTE60366-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338711982445,"sku":"KTE60366-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338712015213,"sku":"KTE60366-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/human-protein-phosphatase-slingshot-homolog-1-ssh1-elisa-kit-bhe13702583","provider":"BioHippo","version":"1.0","type":"link"}