{"product_id":"human-protein-phosphatase-slingshot-homolog-2-ssh2-elisa-kit-bhe13702584","title":"Human Protein phosphatase Slingshot homolog 2 (SSH2) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Protein phosphatase Slingshot homolog 2 (SSH2) ELISA Kit has high sensitivity and excellent specificity for detection of Human SSH2. No significant cross-reactivity or interference between Human SSH2 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eTwo of the human proteins, SSH1L and SSH2, were enzymatically active when reacted with an artificial substrate, p-nitrophenyl phosphate. SSH3 did not exhibit activity toward p-nitrophenyl phosphate, and its expression did not reduce the level of P-cofilin in COS-7 cells. In mammalian cells, SSH1L and SSH2 suppressed LIMK1-induced actin reorganization. Furthermore, ssh, SSH1L, and SSH2 dephosphorylated P-cofilin in cultured cells and in cell-free assays. SSH1 encodes 3 isoforms, SSH1L, SSH1S, and SSH1B, and SSH2 encodes 2 isoforms, SSH2 and SSH2B. The SSH3 protein has 471 amino acids. Besides the catalytic domain, 2 other domains are conserved between Drosophila ssh and the human SSHs (domains A and B) and are unique to the SSH family.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338596442477,"sku":"KTE60367-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338711556461,"sku":"KTE60367-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338711589229,"sku":"KTE60367-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338711621997,"sku":"KTE60367-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60367.png?v=1778954651","url":"https:\/\/www.ebiohippo.com\/products\/human-protein-phosphatase-slingshot-homolog-2-ssh2-elisa-kit-bhe13702584","provider":"BioHippo","version":"1.0","type":"link"}