{"product_id":"human-protein-phosphatase-slingshot-homolog-3-ssh3-elisa-kit-bhe13702585","title":"Human Protein phosphatase Slingshot homolog 3 (SSH3) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Protein phosphatase Slingshot homolog 3 (SSH3) ELISA Kit has high sensitivity and excellent specificity for detection of Human SSH3. No significant cross-reactivity or interference between Human SSH3 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe ADF (actin-depolymerizing factor)\/cofilin family is composed of stimulus-responsive mediators of actin dynamics. ADF\/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1). The SSH family appears to play a role in actin dynamics by reactivating ADF\/cofilin proteins in vivo.\u003c\/p\u003e\u003cp\u003eTranscript analysis suggested that at least 6 polypeptides would be produced from these genes. SSH1 encodes 3 isoforms, SSH1L, SSH1S, and SSH1B, and SSH2 encodes 2 isoforms, SSH2 and SSH2B. The SSH3 protein has 471 amino acids. Besides the catalytic domain, 2 other domains are conserved between Drosophila ssh and the human SSHs (domains A and B) and are unique to the SSH family.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338596213101,"sku":"KTE60368-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338710966637,"sku":"KTE60368-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338710999405,"sku":"KTE60368-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338711032173,"sku":"KTE60368-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60368.png?v=1778954650","url":"https:\/\/www.ebiohippo.com\/products\/human-protein-phosphatase-slingshot-homolog-3-ssh3-elisa-kit-bhe13702585","provider":"BioHippo","version":"1.0","type":"link"}