{"product_id":"human-protein-quaking-qki-elisa-kit-bhe13703222","title":"Human Protein quaking (QKI) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Protein quaking (QKI) ELISA Kit has high sensitivity and excellent specificity for detection of Human QKI. No significant cross-reactivity or interference between Human QKI and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eQKI belongs to a family of RNA-binding proteins called STAR proteins for Signal Transduction and Activation of RNA. They have an HNRNPK homology (KH) domain embedded in a 200-amino acid region called the GSG domain. Other members of this family include SAM68 (KHDRBS1) and SF1.\u003c\/p\u003e\u003cp\u003eThe QKI gene is implicated as being important in schizophrenia, and QKI controls translation of many oligodendrocyte-related genes.The balance between the nuclear and cytoplasmic isoforms of Qk1 controlled the nuclear export of Mbp mRNAs and the cellular localization of the 17- and 21.5-kD Mbp isoforms. Overexpression of Qki-5 in cultured rodent oligodendrocytes recreated the Mbp defects observed in qk(v) mice, with retention of Mbp in the nucleus.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338616988013,"sku":"KTE61006-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338774733165,"sku":"KTE61006-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338774765933,"sku":"KTE61006-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338774798701,"sku":"KTE61006-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/human-protein-quaking-qki-elisa-kit-bhe13703222","provider":"BioHippo","version":"1.0","type":"link"}