{"product_id":"human-ptpn22-protein-tyrosine-phosphatase-non-receptor-type-22-elisa-kit-bhe10807185","title":"Human PTPN22 (Protein tyrosine phosphatase, non-receptor type 22) ELISA Kit","description":"\u003ch2\u003eBackground\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003ehuman PTPN22 (Protein tyrosine phosphatase, non-receptor type 22)\u003c\/strong\u003e is a molecular target commonly studied in signal transduction and metabolism research. Receptors translate extracellular cues into intracellular signaling programs and may be regulated through expression, ligand binding, shedding, and endocytosis.\u003c\/p\u003e\u003ch2\u003eBiological role and mechanism\u003c\/h2\u003e\u003cp\u003eThe biological role of PTPN22 is typically understood in terms of its molecular category and interaction network. Depending on the model system, it may participate in cell–cell communication, intracellular signaling, enzymatic processing, or regulation of gene expression programs. Mechanistic interpretation is often strengthened by considering upstream regulators and downstream readouts rather than relying on a single marker.\u003c\/p\u003e\u003cp\u003eExpression and abundance of PTPN22 can vary by tissue, cell type, and physiological state. In many systems, levels are influenced by factors such as developmental stage, immune activation, metabolic status, and cellular stress. Because sample matrix and pre-analytical handling can affect measured concentrations, interpretation is typically strongest when experiments keep collection and processing consistent across groups.\u003c\/p\u003e\u003ch2\u003eNomenclature and related terms\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003ePTPN22 (Protein tyrosine phosphatase, non-receptor type 22)\u003c\/strong\u003e may also be referenced as \u003cstrong\u003eTyrosine-protein phosphatase non-receptor type 22\u003c\/strong\u003e, \u003cstrong\u003eHematopoietic cell protein-tyrosine phosphatase 70Z-PEP\u003c\/strong\u003e, and \u003cstrong\u003eLymphoid phosphatase\u003c\/strong\u003e in the literature or in databases. When comparing results across studies, confirm that the reported analyte refers to the same molecule, species context, and molecular form (e.g., precursor vs mature protein, or soluble vs membrane-associated forms).\u003c\/p\u003e\u003ch2\u003eWhy it matters in research\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eUnderstanding how PTPN22 relates to energy homeostasis, glucose and lipid metabolism, insulin sensitivity and endocrine regulation, and adipose–liver crosstalk in signal transduction and metabolism research.\u003c\/li\u003e\n\u003cli\u003eInterpreting shifts in PTPN22 levels alongside other pathway components or complementary markers.\u003c\/li\u003e\n\u003cli\u003eConnecting molecular changes to phenotypes such as inflammation, remodeling, metabolism shifts, or cell-state transitions (context-dependent).\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eMolecular forms and interpretation\u003c\/h2\u003e\u003cp\u003eFor some targets, isoforms, proteolytic processing, or post-translational modifications (such as phosphorylation or glycosylation) can influence function and apparent abundance. If multiple molecular forms are expected in your model, align interpretation with the form most relevant to the biological question.\u003c\/p\u003e\u003ch2\u003eDisease and translational relevance\u003c\/h2\u003e\u003cp\u003ePTPN22 has been investigated across diverse physiological and disease contexts, and changes in its abundance have been reported in areas aligned with signal transduction and metabolism studies. These associations are interpreted as research findings rather than diagnostic or therapeutic claims, and they should be evaluated alongside model-specific covariates and study design.\u003c\/p\u003e","brand":"Fine Test","offers":[{"title":"96 T","offer_id":52975396847981,"sku":"EH11526-96T","price":520.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/elisa_43d83f39-2917-4aa7-96b9-986dad8363ee.jpg?v=1769598983","url":"https:\/\/www.ebiohippo.com\/products\/human-ptpn22-protein-tyrosine-phosphatase-non-receptor-type-22-elisa-kit-bhe10807185","provider":"BioHippo","version":"1.0","type":"link"}