{"product_id":"human-rac-beta-serine-threonine-protein-kinase-akt2-elisa-kit-bhe13702858","title":"Human RAC-beta serine\/threonine-protein kinase (AKT2) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman RAC-beta serine\/threonine-protein kinase (AKT2) ELISA Kit has high sensitivity and excellent specificity for detection of Human AKT2. No significant cross-reactivity or interference between Human AKT2 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eAKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine\/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phosphorylating several known proteins. Mice lacking Akt2 have a normal body mass, but display a profound diabetic phenotype, indicating that Akt2 plays a key role in signal transduction downstream of the insulin receptor. Mice lacking Akt2 show worse outcome in breast cancer initaited by the large T antigen as well as the neu oncogene.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338605617517,"sku":"KTE60642-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338738688365,"sku":"KTE60642-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338738721133,"sku":"KTE60642-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338738753901,"sku":"KTE60642-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/human-rac-beta-serine-threonine-protein-kinase-akt2-elisa-kit-bhe13702858","provider":"BioHippo","version":"1.0","type":"link"}