{"product_id":"human-receptor-type-tyrosine-protein-phosphatase-eta-ptprj-elisa-kit-bhe13703263","title":"Human Receptor-type tyrosine-protein phosphatase eta (PTPRJ) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Receptor-type tyrosine-protein phosphatase eta (PTPRJ) ELISA Kit has high sensitivity and excellent specificity for detection of Human PTPRJ. No significant cross-reactivity or interference between Human PTPRJ and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eis a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This PTP is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 (PLCG1) and Linker for Activation of T Cells (LAT). This PTP was also found to dephosphorylate PDGF beta receptor, and may be involved in UV-induced signal transduction.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338618921325,"sku":"KTE61047-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338778534253,"sku":"KTE61047-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338778567021,"sku":"KTE61047-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338778599789,"sku":"KTE61047-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE61047.png?v=1778954719","url":"https:\/\/www.ebiohippo.com\/products\/human-receptor-type-tyrosine-protein-phosphatase-eta-ptprj-elisa-kit-bhe13703263","provider":"BioHippo","version":"1.0","type":"link"}