{"product_id":"human-regulator-of-g-protein-signaling-1-rgs1-elisa-kit-bhe13703017","title":"Human Regulator of G-protein signaling 1 (RGS1) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman Regulator of G-protein signaling 1 (RGS1) ELISA Kit has high sensitivity and excellent specificity for detection of Human RGS1. No significant cross-reactivity or interference between Human RGS1 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eRegulator of G-protein signaling 1 is a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta\/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.B-cell specific. Expression is relatively low in B-cells and chronic lymphocytic leukemia B-cells; however, in other types of malignant B-cell such as non-Hodgkin's lymphoma and hairy cell leukemia, expression is constitutively high.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338610499949,"sku":"KTE60801-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338754908525,"sku":"KTE60801-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338754941293,"sku":"KTE60801-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338754974061,"sku":"KTE60801-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60801.png?v=1778954699","url":"https:\/\/www.ebiohippo.com\/products\/human-regulator-of-g-protein-signaling-1-rgs1-elisa-kit-bhe13703017","provider":"BioHippo","version":"1.0","type":"link"}