{"product_id":"human-s100-calcium-binding-protein-a8-s100a8-elisa-kit-bhe13702976","title":"Human S100 Calcium Binding Protein A8 (S100A8) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eHuman S100 Calcium Binding Protein A8 (S100A8) ELISA Kit has high sensitivity and excellent specificity for detection of Human S100A8. No significant cross-reactivity or interference between Human S100A8 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eS100A8, a protein associated with a wide variety of inflammatory conditions, is heavily over-expressed in association with inflammation. Human S100A8 possesses neutrophil-repelling properties that result in an anti-inflammatory effect in vivo. The chemotactic activity of S100A8 on neutrophils was tested in Transwell chemotaxis assays. Analysis of the data indicates that S100A8 causes a repulsion of peripheral neutrophils, an activity that S100A8 loses upon its oxidation. S100A8 causes a strong anti-inflammatory effect in the rat air-pouch model of inflammation in vivo. These data highlight a naturally occurring novel anti-inflammatory pathway and provide potential molecular targets for the development of novel anti-inflammatory therapeutics.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338609418605,"sku":"KTE60760-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338750091629,"sku":"KTE60760-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338750124397,"sku":"KTE60760-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338750157165,"sku":"KTE60760-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE60760.png?v=1778954689","url":"https:\/\/www.ebiohippo.com\/products\/human-s100-calcium-binding-protein-a8-s100a8-elisa-kit-bhe13702976","provider":"BioHippo","version":"1.0","type":"link"}